Jiri Aubrecht Selected Research

CP-809,101

6/2007

Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel 5-hydroxytryptamine2c receptor agonist for the treatment of obesity: role of metabolic activation.

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Jiri Aubrecht Research Topics

Disease

8	Chemical and Drug Induced Liver Injury 01/2020 - 01/2013
3	Neoplasms (Cancer) 11/2011 - 01/2004
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 01/2020
2	Crohn Disease (Crohn's Disease) 01/2021 - 01/2020
2	Poisoning 02/2020 - 04/2013
2	Necrosis 01/2020 - 04/2014
2	Liver Diseases (Liver Disease) 01/2018 - 01/2017
2	Infections 01/2017 - 04/2014
2	Carcinogenesis 04/2009 - 04/2005
1	Ulcerative Colitis 01/2021
1	Fibrosis (Cirrhosis) 02/2020
1	Acute Liver Failure (Fulminant Hepatic Failure) 02/2020
1	Disease Progression 01/2020
1	Parkinson Disease (Parkinson's Disease) 11/2019
1	Parkinsonian Disorders (Parkinsonism) 11/2019
1	End Stage Liver Disease 01/2019
1	Hepatitis B 01/2017
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2017
1	Type 2 Diabetes Mellitus (MODY) 01/2017
1	Acute Kidney Injury (Acute Renal Failure) 04/2014
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2013
1	Cross Infection (Nosocomial Infection) 06/2013
1	Starvation 09/2007
1	Body Weight (Weight, Body) 06/2007
1	Obesity 06/2007
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2004

Drug/Important Bio-Agent (IBA)

12	Biomarkers (Surrogate Marker)IBA 01/2020 - 04/2009
5	Acetaminophen (Paracetamol)FDA LinkGeneric 02/2020 - 04/2013
3	MicroRNAs (MicroRNA)IBA 02/2020 - 02/2015
3	Bile Acids and Salts (Bile Acids)IBA 01/2019 - 01/2014
2	Alanine Transaminase (SGPT)IBA 01/2020 - 04/2013
2	Polymyxins (Polymyxin)IBA 04/2014 - 06/2013
2	Glutamate DehydrogenaseIBA 07/2013 - 04/2013
2	CarcinogensIBA 11/2011 - 03/2009
2	DNA (Deoxyribonucleic Acid)IBA 04/2005 - 01/2004
1	vedolizumabIBA 01/2021
1	K-18 conjugate (K18)IBA 01/2019
1	PF-04895162IBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2014
1	Peptides (Polypeptides)IBA 04/2014
1	Polymyxin B (Aerosporin)FDA LinkGeneric 04/2014
1	AminoglycosidesIBA 04/2014
1	Purine-Nucleoside PhosphorylaseIBA 04/2013
1	Malate Dehydrogenase (Dehydrogenase, Malate)IBA 04/2013
1	Histidine (L-Histidine)FDA Link 09/2007
1	CP-809,101IBA 06/2007

Therapy/Procedure

1	Therapeutics 01/2020
1	Drug Therapy (Chemotherapy) 12/2013